The article presents several adaptive fuzzy hedge logics. These logics are designed to perform a specific kind of hedge detection. Given a premise set Γ that represents a series of communicated statements, the logics can check whether some predicate occurring in Γ may be interpreted as being (implicitly) hedged by technically, strictly speaking or loosely speaking, or simply non-hedged. The logics take into account both the logical constraints of the premise set as well as conceptual information concerning the meaning of (...) potentially hedged predicates (stored in the memory of the interpreter in question). The proof theory of the logics is non-monotonic in order to enable the logics to deal with possible non-monotonic interpretation dynamics (this is illustrated by means of several concrete proofs). All the adaptive fuzzy hedge logics are also sound and strongly complete with respect to their [0,1]-semantics. (shrink)

The article presents several adaptive fuzzy hedge logics. These logics are designed to perform a specific kind of hedge detection. Given a premise set Γ that represents a series of communicated statements, the logics can check whether some predicate occurring in Γ may be interpreted as being (implicitly) hedged by technically, strictly speaking or loosely speaking, or simply non-hedged. The logics take into account both the logical constraints of the premise set as well as conceptual information concerning the meaning of (...) potentially hedged predicates (stored in the memory of the interpreter in question). The proof theory of the logics is non-monotonic in order to enable the logics to deal with possible non-monotonic interpretation dynamics (this is illustrated by means of several concrete proofs). All the adaptive fuzzy hedge logics are also sound and strongly complete with respect to their [0,1]-semantics. (shrink)

In this paper, we present a generic format for adaptive vague logics. Logics based on this format are able to (1) identify sentences as vague or non-vague in light of a given set of premises, and to (2) dynamically adjust the possible set of inferences in accordance with these identifications, i.e. sentences that are identified as vague allow only for the application of vague inference rules and sentences that are identified as non-vague also allow for the application of some extra (...) set of classical logic rules. The generic format consists of a set of minimal criteria that must be satisfied by the vague logic in casu in order to be usable as a basis for an adaptive vague logic. The criteria focus on the way in which the logic deals with a special ⊡-operator. Depending on the kind of logic for vagueness that is used as a basis for the adaptive vague logic, this operator can be interpreted as completely true, definitely true, clearly true, etc. It is proven that a wide range of famous logics for vagueness satisfies these criteria when extended with a specific ⊡-operator, e.g. fuzzy basic logic and its well known extensions, cf. [7], super- and subvaluationist logics, cf. [6], [9], and clarity logic, cf. [13]. Also a fuzzy logic is presented that can be used for an adaptive vague logic that can deal with higher-order vagueness. To illustrate the theory, some toy-examples of adaptive vague proofs are provided. (shrink)

The article presents several adaptive fuzzy hedge logics . These logics are designed to perform a specific kind of hedge detection. Given a premise set Γ that represents a series of communicated statements, the logics can check whether some predicate occurring in Γ may be interpreted as being (implicitly) hedged by technically , strictly speaking or loosely speaking , or simply non-hedged. The logics take into account both the logical constraints of the premise set as well as conceptual information concerning (...) the meaning of potentially hedged predicates (stored in the memory of the interpreter in question). The proof theory of the logics is non-monotonic in order to enable the logics to deal with possible non-monotonic interpretation dynamics (this is illustrated by means of several concrete proofs). All the adaptive fuzzy hedge logics are also sound and strongly complete with respect to their [0,1]-semantics. (shrink)

In this paper, we present a generic format for adaptive vague logics. Logics based on this format are able to (1) identify sentences as vague or non-vague in light of a given set of premises, and to (2) dynamically adjust the possible set of inferences in accordance with these identifications, i.e. sentences that are identified as vague allow only for the application of vague inference rules and sentences that are identified as non-vague also allow for the application of some extra (...) set of classical logic rules. The generic format consists of a set of minimal criteria that must be satisfied by the vague logic in casu in order to be usable as a basis for an adaptive vague logic. The criteria focus on the way in which the logic deals with a special ⊡-operator. Depending on the kind of logic for vagueness that is used as a basis for the adaptive vague logic, this operator can be interpreted as completely true, definitely true, clearly true , etc. It is proven that a wide range of famous logics for vagueness satisfies these criteria when extended with a specific ⊡-operator, e.g. fuzzy basic logic and its well known extensions, cf. [7], super- and subvaluationist logics, cf. [6], [9], and clarity logic, cf. [13]. Also a fuzzy logic is presented that can be used for an adaptive vague logic that can deal with higher-order vagueness. To illustrate the theory, some toy-examples of adaptive vague proofs are provided. (shrink)

What became of Erasmus' books? The most famous scholar of his day died in peaceful prosperity and in the company of celebrated and responsible friends. His zeal for useful books was insatiable. Indeed, he had taken care to insure that after his death they would pass to an appreciative noble owner, yet after his death their fate was unknown. Erasmus and His Books provides the most comprehensive evidence available about the books of Erasmus of Rotterdam - the books he owned (...) and his attitude towards them, when and how he acquired them, how he housed, used, and cared for them, and how, from time to time, he disposed of them. Part 1 details the formation, growth, scope, and arrangement of Erasmus' library and opens the door to a new understanding of the more intimate side of his daily life as a scholar at home with his books, friends, publishers, and booksellers. Part 2 presents a carefully annotated catalogue, the Versandliste, of the more than 400 books in Erasmus' possession at one point. Drawing upon his command of bibliographical data and his extensive knowledge of Erasmus' correspondence and related records, Egbertus van Gulik proposes as precise an identification of each of the titles as the evidence will allow."-- Provided by publisher. (shrink)

This article reflects a conversation between Jan G. van der Watt and Stephan Joubert. The article serves as the introduction to the Special Collection: ‘From timely exegesis to contemporary ecclesiology: Relevant hermeneutics and provocative embodiment of faith in a Corona-defined world – Festschrift for Stephan Joubert, sub-edited by Willem Oliver ’. Following a brief bio-statement as introduction, the following issues are discussed: the collection for the Jerusalem church; relevance of theology for society; social-scientific exegesis; the ancient concept of (...) grace; Bible translation in South Africa; public theology on the electronic platform; biblical examples of leadership and electronic media in religious activities and education.Contribution: This Festschrift represents current trends in biblical scholarship and ecclesial leadership. It contributes to the public discourse in church and society, especially the role of the electronic media in current Fourth Industrial Revolution. (shrink)

Both the concept of a Darwinian tree of life (TOL) and the possibility of its accurate reconstruction have been much criticized. Criticisms mostly revolve around the extensive occurrence of lateral gene transfer (LGT), instances of uptake of complete organisms to become organelles (with the associated subsequent gene transfer to the nucleus), as well as the implications of more subtle aspects of the biological species concept. Here we argue that none of these criticisms are sufficient to abandon the valuable TOL concept (...) and the biological realities it captures. Especially important is the need to conceptually distinguish between organismal trees and gene trees, which necessitates incorporating insights of widely occurring LGT into modern evolutionary theory. We demonstrate that all criticisms, while based on important new findings, do not invalidate the TOL. After considering the implications of these new insights, we find that the contours of evolution are best represented by a TOL. (shrink)

Neuroscience is a multidisciplinary effort to understand the structures and functions of the brain and brain-mind relations. This effort results in an increasing amount of data, generated by sophisticated technologies. However, these data enhance our descriptive knowledge, rather than improve our understanding of brain functions. This is caused by methodological gaps both within and between subdisciplines constituting neuroscience, and the atomistic approach that limits the study of macro- and mesoscopic issues. Whole-brain measurement technologies do not resolve these issues, but rather (...) aggravate them by the complexity problem. The present article is devoted to methodological and epistemic problems that obstruct the development of human neuroscience. We neither discuss ontological questions nor review data, except when it is necessary to demonstrate a methodological issue. As regards intradisciplinary methodological problems, we concentrate on those within neurobiology and psychology. As regards interdisciplinary problems, we suggest that core disciplines of neuroscience can be integrated using systemic concepts that also entail human-environment relations. We emphasize the necessity of a meta-discussion that should entail a closer cooperation with philosophy as a discipline of systematic reflection. The atomistic reduction should be complemented by the explicit consideration of the embodiedness of the brain and the embeddedness of humans. The discussion is aimed at the development of an explicit methodology of integrative human neuroscience, which will not only link different fields and levels, but also help in understanding clinical phenomena. (shrink)

In this theoretical contribution, we interpret the notion of professional development in the light of concepts coming from cognitive development. This brings us to consider teacher training as not only having to allow the elaboration of skills, but also as having to encourage the development of new cognitive structures. We explore the theoretical concepts in relation with certain processes revealed by the reflexive texts of the students. Finally, we propose ways that could foster certain dimensions of global professional development in (...) learners, among which self-regulated learning, the focus on certain concerns and taking into account certain types of information. (shrink)

Our contribution concerns the continuous training of teachers that will be forming future teachers during their traineeship. It aims to describe how the professional development of the trainees’ coaches, both the training supervisors as well as the supervisors form the trainees’ schools, was used during a course proposed by a university and during meetings where practices were shared by the participants. In this manner, we identified the ideal moments for development of the trainees, as well as the most important levers (...) for the transformation of the coaches. We paid particular attention to the reflexive contract co-defined by the group, as well as to the principle of social moderation at the heart of the collaborative group’s dynamic. (shrink)

In this paper, we present a generic format for adaptive vague logics. Logics based on this format are able to (1) identify sentences as vague or non-vague in light of a given set of premises, and to (2) dynamically adjust the possible set of inferences in accordance with these identifications, i.e. sentences that are identified as vague allow only for the application of vague inference rules and sentences that are identified as non-vague also allow for the application of some extra (...) set of classical logic rules. The generic format consists of a set of minimal criteria that must be satisfied by the vague logic in casu in order to be usable as a basis for an adaptive vague logic. The criteria focus on the way in which the logic deals with a special ⊡-operator. Depending on the kind of logic for vagueness that is used as a basis for the adaptive vague logic, this operator can be interpreted as completely true, definitely true, clearly true, etc. It is proven that a wide range of famous logics for vagueness satisfies these criteria when extended with a specific ⊡-operator, e.g. fuzzy basic logic and its well known extensions, cf. [7], super- and subvaluationist logics, cf. [6], [9], and clarity logic, cf. [13]. Also a fuzzy logic is presented that can be used for an adaptive vague logic that can deal with higher-order vagueness. To illustrate the theory, some toy-examples of adaptive vague proofs are provided. (shrink)

This paper concerns model-checking of fragments and extensions of CTL* on infinite-state Presburger counter systems, where the states are vectors of integers and the transitions are determined by means of relations definable within Presburger arithmetic. In general, reachability properties of counter systems are undecidable, but we have identified a natural class of admissible counter systems (ACS) for which we show that the quantification over paths in CTL* can be simulated by quantification over tuples of natural numbers, eventually allowing translation of (...) the whole Presburger-CTL* into Presburger arithmetic, thereby enabling effective model checking. We provide evidence that our results are close to optimal with respect to the class of counter systems described above. (shrink)

Life-science phenomena are often explained by specifying the mechanisms that bring them about. The new mechanistic philosophers have done much to substantiate this claim and to provide us with a better understanding of what mechanisms are and how they explain. Although there is disagreement among current mechanists on various issues, they share a common core position and a seeming commitment to some form of scientific realism. But is such a commitment necessary? Is it the best way to go about mechanistic (...) explanation? In this article, we propose an alternative antirealist account that also fits explanatory practice in the life sciences. We pay special attention to mechanistic models, i.e. scientific models that involve a mechanism, and to the role of coherence considerations in building such models. To illustrate our points, we consider the mechanism for the action potential. 1 Introduction2 Some Core Features of Mechanistic Explanation3 Scientific Realism and Mechanistic Explanation4 Antirealist Mechanistic Explanation: The Case of the Action Potential5 Some Outstanding Issues for the Antirealist Mechanist6 Two Problems for the Realist Mechanist7 Conclusions. (shrink)

This thought-provoking book discusses the concept of progress in economics and investigates whether any advance has been made in its different spheres of research. The authors look back at the history, successes and failures of their respective fields and thoroughly examine the notion of progress from an epistemological and methodological perspective. The idea of progress is particularly significant as the authors regard it as an essentially contested concept which can be defined in many ways – theoretically or empirically; locally or (...) globally; or as encouraging or impeding the existence of other research traditions. The authors discuss the idea that for progress to make any sense there must be an accumulation of knowledge built up over time rather than the replacement of ideas by each successive generation. Accordingly, they are not concerned with estimating the price of progress, reminiscing in the past, or assessing what has been lost. Instead they apply the complex mechanisms and machinery of the discipline to sub-fields such as normative economics, monetary economics, trade and location theory, Austrian economics and classical economics to critically assess whether progress has been made in these areas of research. -/- Bringing together authoritative and wide-ranging contributions by leading scholars, this book will challenge and engage those interested in philosophy, economic methodology and the history of economic thought. It will also appeal to economists in general who are interested in the advancement of their profession. (shrink)

In previous studies, we found that bodily symptoms can be learned in a differential conditioning paradigm, using odors as conditioned stimuli and CO2-enriched air as unconditioned stimulus . However, this only occurred when the odor CS had a negative valence , and tended to be more pronounced in persons scoring high for Negative Affectivity . This paper considers the necessity and/or sufficiency of awareness of the CS–US contingency in three studies using this paradigm. The relation between contingency awareness and the (...) selective conditioning effect, and between contingency awareness and NA was also considered. Both self reported symptoms and respiratory physiology served as dependent variables. A learning effect on symptoms was found only for participants aware of the CS–US contingency, but not all participants reporting contingency awareness showed a learning effect. No conditioning effects appeared on the physiological measures. Also contingency awareness did not account for the selective conditioning effect, and did not interact with NA. Overall, the necessity but insufficiency hypotheses can only be withhold for group data and not for individual data. (shrink)

Within current debates about the future impact of Artificial Intelligence on human society, roughly three different perspectives can be recognised: the technology-centric perspective, claiming that AI will soon outperform humankind in all areas, and that the primary threat for humankind is superintelligence; the human-centric perspective, claiming that humans will always remain superior to AI when it comes to social and societal aspects, and that the main threat of AI is that humankind’s social nature is overlooked in technological designs; and the (...) collective intelligence-centric perspective, claiming that true intelligence lies in the collective of intelligent agents, both human and artificial, and that the main threat for humankind is that technological designs create problems at the collective, systemic level that are hard to oversee and control. The current paper offers the following contributions: a clear description for each of the three perspectives, along with their history and background; an analysis and interpretation of current applications of AI in human society according to each of the three perspectives, thereby disentangling miscommunication in the debate concerning threats of AI; and a new integrated and comprehensive research design framework that addresses all aspects of the above three perspectives, and includes principles that support developers to reflect and anticipate upon potential effects of AI in society. (shrink)

This article provides a substantive discussion of the relevance of the history of archeology to the history of science. At the same time, the article introduces the papers contained in this special issue as exemplars of this relevance. To make its case, the article moves through various themes in the history of archeology that overlap with key issues in the history of science. The article discusses the role and tension of regimes of science in antiquarian and archeological practices, and also (...) considers issues of scale and place, particularly in relation to the field. Additionally, the piece attends to issues of professionalization and the constitution of an archeological public, at the same time as discussing issues of empire, colonialism, and the circulation of knowledge. Meanwhile, enriching discussions within and beyond the history of science, the article discusses the history of archeology and its relationship with museums, collecting, and material culture and materiality. Finally, the piece discusses the relationship of the history of archeology with wider discussions about scientific ethics. In conclusion, the article questions whether we should speak of ‘the history of archeology’ at all. (shrink)

Over three centuries after the 1711 discovery in the choir of Notre-Dame in Paris of a square-section stone bas-relief with depictions of several deities, both Gaulish and Roman, the blocks comprising it were analyzed as a symbol of Parisian power, if not autonomy, vis-à-vis the Roman Empire. Variously considered as local, national, or imperial representations, the blocks were a constant object of admiration, interrogation, and speculation among antiquarians of the Republic of Letters. They were also boundary objects – products of (...) the emergence of a Parisian archeology dated from 1711. If this science reflected the tensions and ambiguities of a local regime of knowledge situated in a national context, it also helped to coordinate archeological work between different institutions and actors. This paper would like to assess the specific role played by the Pillar of the Boatmen as a fetish object in this process. To what extent could an archeological artifact influence this reshaping of urban representation, this change of scales? By following the three-century career of the pillar’s blocks as composite objects, which some have identified as merely stones or a column, it is possible to understand the multiple dimensions that defined the object as archeological – as an artifact that contributed to the relocating of the historical city center – and the multiple approaches that transform existing remains into knowledgeable objects. (shrink)

The South African government’s COVID-19 pandemic risk mitigation strategies significantly limited social contact, which necessitated a novel approach to existing face-to-face career guidance practices. The Grade 9 Career Guidance Project, originally developed as a group-based career development intervention, required radical adaptation into a self-directed, manualized format to offer career guidance to Grade 9 learners from low-income communities amid a global pandemic. The adaptation and continuation of the project was deemed essential as secondary school learners in low-income communities have limited career (...) guidance support. Furthermore, a close collaboration with the teachers at eight resource-constrained South African secondary schools was vital for successful implementation. To assess the success of the adaptation to a self-directed format, a mixed-methods design was employed, and Life Orientation teachers’ evaluative feedback was solicited. Favorable quantitative results were obtained; majority of teachers agreed that learners enjoyed the booklet and that it was deemed an adequate substitute to the previous contact-based format of the Career Guidance Project. This was also confirmed by the qualitative findings revealing teachers’ satisfaction with the booklet’s content, specifically that the booklet is complementary to the Life Orientation curriculum. Qualitative findings identified specific contextual barriers that contributed to some learners struggling to use the booklet optimally. The results suggest that it is feasible and acceptable to implement a self-directed career guidance intervention among secondary school learners amid a global pandemic. Teachers recommended ways to integrate the booklet, resources, and contact sessions as a preferred way forward. These findings have important implications for similar resource-constrained settings that may not have readily access to in-person career guidance and counseling human development. (shrink)

Human Biological Materials (HBMs) are an invaluable resource in biomedical research.ObjectiveTo determine if researchers and a Research Ethics Committee (REC) at a South African institution addressed ethical issues pertaining to HBMs in collaborative research with developed countries.Study DesignEthically approved retrospective cross‐sectional descriptive audit.ResultsOf the 1305 protocols audited, 151 (11.57%) fulfilled the study's inclusion criteria. Compared to other developed countries, a majority of sponsors (90) were from the USA (p = 0.0001). The principle investigators (PIs) in all 151 protocols informed the (...) REC of their intent to store HBMs. Only 132 protocols informed research participants (P < 0.0001). In 148 protocols informed consent (IC) was obtained from research participants, 116 protocols (76.8%) solicited broad consent compared to specific consent (32; 21.2%) [p < 0.0001]. In 105 cases a code was used to maintain confidentiality. HBMs were anonymised in 14 protocols [p < 0.0001]. More protocols informed the REC (90) than the research participants (67) that HBMs would be exported (p = 0.011). Export permits (EPs) and Material Transfer Agreements (MTAs) were not available in 109 and 143 protocols, respectively.ConclusionsResearchers and the REC did not adequately address the inter‐related ethical and regulatory issues pertaining to HBMs. There was a lack of congruence between the ethical guidelines of developed countries and their actions which are central to the access to HBMs in collaborative research. HBMs may be leaving South Africa without EPs and MTAs during the process of international collaborative research. (shrink)

Amsterdam University Press is a leading publisher of academic books, journals and textbooks in the Humanities and Social Sciences. Our aim is to make current research available to scholars, students, innovators, and the general public. AUP stands for scholarly excellence, global presence, and engagement with the international academic community.

The social construction of reality is influenced extensively by the mass media. Commercialised images of masculinity, including discourses to interpret it, are continuously reflected and/or created by sources of mass media, in a myriad of ways. These images are subjectively loaded, but still effectively communicate to us, and even entice and persuade us. It furthermore wields extensive power over men - especially over their self-images, passions, and egos. In this article, dominating images and discourses concerning manhood and male identity - (...) particularly those displayed in men's health magazines - were critically examined. This was done through a thematic analysis of 123 issues of MHM cover pages. The investigation showed that MHM is infused with traditional masculine ideology. Moreover, MHM fails to confront discourses that endorse hegemonic masculinity, for the sake of holistic health. It was suggested that a sober, precautionary, health strategy should challenge men to critically engage with MHM's reigning creed: 'big, hard and up'. This creed incites a utilitarian view of sexuality within a culture of performance-driven masculinity, which subsequently fuels anxieties that can lead to unhealthy issues, such as body image dissatisfaction. From a pastoral care perspective, it was asserted that Christian men need to search for alternative ways to instigate their capacity to experience and facilitate authentic intimacy, in order to work toward the social construction of more balanced and healthy discourses on male identity. (shrink)

Depuis quelques années, un renouveau historiographique s'est amorcé dans le champ des recherches sur l'ancienne Compagnie de Jésus autour de la production des savoirs. Dans cet article, on s'est attaché à saisir la place, les modalités et les enjeux d'une reconnaissance des pratiques littéraires jésuites en France entre 1620 et 1720, en essayant de montrer les tentatives de constitution d'un apostolat littéraire. Deux approches sont ici proposées: l'une strictement institutionnelle qui essaie de mesurer l'importance du travail intellectuel dans l'espace des (...) charges à l'intérieur de l'Ordre; une autre davantage centrée sur la communication sociale de l'Ordre à travers la discussion de plusieurs dossiers de la polémique antijésuite. (shrink)

In this essay, I will argue that a political theology of human work can provide the sacramental principle underlying the theology of labor. This principle could complement the foundations of Catholic social teaching, since the sacramental aspects of work have not been made very explicit in the ethical framework of the Church's theology of work. The view of labor as the active participation in God's future is an important aspect of such a theology. In order to serve as a foundation (...) for faith-based labor organizing, I will claim that it needs to be complemented by a sacramental view of labor as art, a labor-aesthetic that undergirds a labor-ethic, in which labor itself becomes a sign and instrument of the way the Church becomes God's work in the world. First, I will sketch an outline of some of the major positions on labor in modern Catholic theology. Then, I will draw on the writings of the British poet and painter David Jones to explore a sacramental view of human work, arguing that a sacramental view of work could support the Church's social criticism of laborer's circumstances. (shrink)

Developmental research suggests that young children tend to value dominant individuals over subordinates. This research, however, has nearly exclusively been carried out in Western cultures, and cross-cultural research among adults has revealed cultural differences in the valuing of dominance. In particular, it seems that Japanese culture, relative to many Western cultures, values dominance less. We conducted two experiments to test whether this difference would be observed in preschoolers. In Experiment 1, preschoolers in France and in Japan were asked to identify (...) with either a dominant or a subordinate. French preschoolers identified with the dominant, but Japanese preschoolers were at chance. Experiment 2 revealed that Japanese preschoolers were more likely to believe a subordinate than a dominant individual, both compared to chance and compared to previous findings among French preschoolers. The convergent results from both experiments thus reveal an early emerging cross-cultural difference in the valuing of dominance. (shrink)

Current views of the control of complex, purposeful movements acknowledge that organizational processes must reconcile multiple concerns. The central priority is of course accomplishing the actor's goal. But in specifying the manner in which this occurs, the action plan must accommodate such factors as the interaction of mechanical forces associated with the motion of a multilinked system (classical mechanics) and, in many cases, intrinsic bias toward preferred movement patterns, characterized by so‐called “coordination dynamics.” The most familiar example of the latter (...) is the symmetry constraint, where spatial trajectories and/or temporal landmarks (e.g., reversal points) of concurrentlymoving body segments (limbs, digits, etc.) exhibit mutual attraction. The natural coordination tendencies that emerge through these constraints can facilitate or hinder motor control, depending on the degree of congruency with the desired movement pattern. Motor control theorists have long recognized the role of classical mechanics in theories of movement organization, but an appreciation of the importance of intrinsic interlimb bias has been gained only recently.Although detailed descriptions of temporal coordination dynamics have been provided, systematic attempts to identify additional salient dimensions of interlimb constraint have been lacking. We develop and implement here a novel method for examining this problem by exploiting two robust principles of psychomotor behavior, the symmetry constraint and the Two‐Thirds Power Law. Empirical evidence is provided that the relative spatial patterns of concurrently moving limbs are naturally constrained in much the same manner as previously identified temporal constraints and, further, that apparent velocity interference is an indirect, secondary consequence of primary spatial assimilation. The theoretical implications of spatial interference are elaborated with respect to movement organization and motor learning. The need to carefully consider the appropriate dimensions with which to characterize coordination dynamics is also discussed. (shrink)

Brain imaging studies have consistently shown subgenual Anterior Cingulate Cortical (sgACC) involvement in emotion processing. COMT Val158 and Met158 polymorphisms may influence such emotional brain processes in specific ways. Given that resting-state fMRI (rsfMRI) may increase our understanding on brain functioning, we integrated genetic and rsfMRI data and focused on sgACC functional connections. No studies have yet investigated the influence of the COMT Val158Met polymorphism (rs4680) on sgACC resting-state functional connectivity (rsFC) in healthy individuals. A homogeneous group of sixty-one Caucasian (...) right-handed healthy female university students, all within the same age range, underwent rsfMRI. Compared to Met158 homozygotes, Val158 allele carriers displayed significantly stronger rsFC between the sgACC and the left parahippocampal gyrus, ventromedial parts of the inferior frontal gyrus, and the nucleus accumbens (NAc). On the other hand, compared to Val158 homozygotes, we found in Met158 allele carriers stronger sgACC rsFC with the medial frontal gyrus, more in particular the anterior parts of the medial orbitofrontal cortex. Although we did not use emotional or cognitive tasks, our sgACC rsFC results point to possible distinct differences in emotional and cognitive processes between Val158 and Met158 allele carriers. However, the exact nature of these directions remains to be determined. (shrink)